K2P16-i7-4

Chemical Structure : K2P16-i7-4

Catalog No.: PC-27005Not For Human Use, Lab Use Only.

K2P16-i7-4 is a potent, selective, reversible inhibitor of two-pore domain K+ (K2P) channel TALK-1 with IC50 of 1.61 uM, enhances [Ca2+]ER storage in T-REx-TALK-1 cells.

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Biological Activity

K2P16-i7-4 is a potent, selective, reversible inhibitor of two-pore domain K+ (K2P) channel TALK-1 with IC50 of 1.61 uM, enhances [Ca2+]ER storage in T-REx-TALK-1 cells.

Physicochemical Properties

M.Wt	409.44
Formula	C22H23N3O5
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	ethyl 5-(2-((2,2-dimethyl-2,3-dihydrobenzofuran-7-yl)oxy)acetamido)pyrazolo[1,5-a]pyridine-3-carboxylate

References

1. Nakhe AY, et al. Mol Pharmacol. 2026 May 15;108(5-6):100130.

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K2P16-i7-4

Biological Activity

Physicochemical Properties

References

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