Chemical Structure : K41498
CAS No.: 434938-41-7
Catalog No.: PC-21400Not For Human Use, Lab Use Only.
K41498 is a potent, highly selective CRF2 receptor antagonist with Ki values of 0.66 nM, 0.62 nM and 425 nM for human CRF2α, CRF2β and CRF1 receptors respectively.
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K41498 is a potent, highly selective CRF2 receptor antagonist with Ki values of 0.66 nM, 0.62 nM and 425 nM for human CRF2α, CRF2β and CRF1 receptors respectively.
M.Wt | 3632.22 | |
Formula | C162H276N48O46 | |
Appearance | Solid | |
Storage |
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Solubility |
10 mM in DMSO |
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Chemical Name/SMILES |
{D-Phe}-His-Leu-Leu-Arg-Lys-{Nle}-Ile-Glu-Ile-Glu-Lys-Gln-Glu-Lys-Glu-Lys-Gln-Gln-Ala-Ala-Asn-Asn-Arg-Leu-Leu-Leu-Asp-Thr-Ile-NH2 |
1. Erspamer V, et al. Naunyn Schmiedebergs Arch Pharmacol. 1980 Jul;312(3):265-70.
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