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K41498

Chemical Structure : K41498

CAS No.: 434938-41-7

K41498 (K 41498)

Catalog No.: PC-21400Not For Human Use, Lab Use Only.

K41498 is a potent, highly selective CRF2 receptor antagonist with Ki values of 0.66 nM, 0.62 nM and 425 nM for human CRF2α, CRF2β and CRF1 receptors respectively.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

K41498 is a potent, highly selective CRF2 receptor antagonist with Ki values of 0.66 nM, 0.62 nM and 425 nM for human CRF2α, CRF2β and CRF1 receptors respectively.

Physicochemical Properties

M.Wt 3632.22
Formula C162H276N48O46
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

{D-Phe}-His-Leu-Leu-Arg-Lys-{Nle}-Ile-Glu-Ile-Glu-Lys-Gln-Glu-Lys-Glu-Lys-Gln-Gln-Ala-Ala-Asn-Asn-Arg-Leu-Leu-Leu-Asp-Thr-Ile-NH2

References

1. Erspamer V, et al. Naunyn Schmiedebergs Arch Pharmacol. 1980 Jul;312(3):265-70.

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