K41498 | CRF2 inhibitor | Probechem Biochemicals

Chemical Structure : K41498

CAS No.: 434938-41-7

K41498 (K 41498)

Catalog No.: PC-21400Not For Human Use, Lab Use Only.

K41498 is a potent, highly selective CRF2 receptor antagonist with Ki values of 0.66 nM, 0.62 nM and 425 nM for human CRF2α, CRF2β and CRF1 receptors respectively.

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Biological Activity

K41498 is a potent, highly selective CRF2 receptor antagonist with Ki values of 0.66 nM, 0.62 nM and 425 nM for human CRF2α, CRF2β and CRF1 receptors respectively.

Physicochemical Properties

M.Wt	3632.22
Formula	C162H276N48O46
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	{D-Phe}-His-Leu-Leu-Arg-Lys-{Nle}-Ile-Glu-Ile-Glu-Lys-Gln-Glu-Lys-Glu-Lys-Gln-Gln-Ala-Ala-Asn-Asn-Arg-Leu-Leu-Leu-Asp-Thr-Ile-NH2

References

1. Erspamer V, et al. Naunyn Schmiedebergs Arch Pharmacol. 1980 Jul;312(3):265-70.

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K41498 (K 41498)

Biological Activity

Physicochemical Properties

References

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