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Chemical Structure : KA2507
CAS No.: 1636894-46-6
Catalog No.: PC-72342Not For Human Use, Lab Use Only.
KA2507 (KA-2507, KA 2507) is a potent and selective inhibitor of HDAC6 with IC50 of 2.5 nM, >300-fold selectivity over other HDACs.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 5 mg | $218 | In stock | |
| 10 mg | $358 | In stock | |
| 25 mg | $568 | In stock | |
| 50 mg | Get quote | ||
| 100 mg | Get quote |
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KA2507 (KA-2507, KA 2507) is a potent and selective inhibitor of HDAC6 with IC50 of 2.5 nM, >300-fold selectivity over other HDACs.
KA2507 demonstrated cellular potency (IC50=150 nM) in a cellular assay measuring induction of acetylated α-tubulin, a marker of HDAC6 inhibition.
KA2507 displays antiproliferative effects against a set of 93 human cancer cells with IC50 of 2-30 uM.
KA2507 inhibits tumor growth in the syngeneic B16-F10 mouse melanoma model.
| M.Wt | 322.328 | |
| Formula | C16H14N6O2 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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| Chemical Name/SMILES |
Benzamide, 4-[(di-2-pyrazinylamino)methyl]-N-hydroxy- |
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1. Apostolia M Tsimberidou, et al. Clin Cancer Res. 2021 Jul 1;27(13):3584-3594.
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