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Chemical Structure : KAB-18
Catalog No.: PC-60678Not For Human Use, Lab Use Only.
A potent, selective, noncompetitive human α4β2 nAChRs negative allosteric modulator with IC50 of 13.5 uM, displays no inhibitory activity on Hα3β4 nAChRs at 100 uM..
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A potent, selective, noncompetitive human α4β2 nAChRs negative allosteric modulator with IC50 of 13.5 uM, displays no inhibitory activity on Hα3β4 nAChRs at 100 uM.
| M.Wt | 413.561 | |
| Formula | C28H31NO2 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Henderson BJ, et al. J Pharmacol Exp Ther. 2010 Sep 1;334(3):761-74.
2. Pavlovicz RE, et al. PLoS One. 2011;6(9):e24949.
3. Henderson BJ, et al. ACS Chem Neurosci. 2012 Sep 19;3(9):682-92.
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