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KBP-5074

Chemical Structure : KBP-5074

CAS No.: 1359969-26-8

KBP-5074 (KBP5074, Ocedurenone)

Catalog No.: PC-35939Not For Human Use, Lab Use Only.

KBP-5074 (KBP5074, Ocedurenone) is a novel non-steroidal, highly selective mineralocorticoid receptor antagonist for the treatment of hypertensive chronic kidney disease.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

    Biological Activity

    KBP-5074 (KBP5074, Ocedurenone) is a novel non-steroidal, highly selective mineralocorticoid receptor antagonist for the treatment of hypertensive chronic kidney disease.

    Physicochemical Properties

    M.Wt 504.031
    Formula C28H30ClN5O2
    Appearance Solid
    CAS No.
    Storage
    Solide Powder
    -20 °C 12 Months; 4°C 6 Months
    In Solvent
    -80 °C 6 Months; -20°C 6 Months
    Shipping
    Solubility

    10 mM in DMSO

    Chemical Name/SMILES

    2-chloro-4-((3R,3aR)-3-cyclopentyl-7-(4-hydroxypiperidine-1-carbonyl)-3,3a,4,5-tetrahydro-2H-pyrazolo[3,4-f]quinolin-2-yl)benzonitrile

    References

    1. Granberg K, et al. J Med Chem. 2018 Dec 31. doi: 10.1021/acs.jmedchem.8b01523.

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