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Chemical Structure : KBP-7018 hydrochloride
Catalog No.: PC-60152Not For Human Use, Lab Use Only.
KBP-7018 hydrochloride is a potent, multikinase inhibitor with IC50 of 10, 7.6 and 25 nM for c-Kit, RET and PDGFRβ, respectively.
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KBP-7018 hydrochloride is a potent, multikinase inhibitor with IC50 of 10, 7.6 and 25 nM for c-Kit, RET and PDGFRβ, respectively.
KBP-7018 also potently inhibits FLT3, VEGFR2, Fyn, PDGFRα and VEGFR2.
KBP-7018 shows promising outcomes for the treatments of idiopathic pulmonary fibrosis (IPF).
| M.Wt | 575.06 | |
| Formula | C31H31ClN4O5 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Huang Z, et al. ACS Med Chem Lett. 2017 Sep 30;8(11):1142-1147.
2. Huang Z, et al. Drug Des Devel Ther. 2015 Aug 5;9:4319-28.
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