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Chemical Structure : KB SRC 4
Catalog No.: PC-62865Not For Human Use, Lab Use Only.
KB SRC 4 (c-Src-IN-4) is a potent, highly selective c-Src kinase inhibitor with Ki of 44 nM, does not inhibit c-Abl up to 125 uM, and binds to c-Src-TM (Q275G, C277Q, F278Y) with similar potency to that of wild-type c-Src.
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KB SRC 4 (c-Src-IN-4) is a potent, highly selective c-Src kinase inhibitor with Ki of 44 nM, does not inhibit c-Abl up to 125 uM, and binds to c-Src-TM (Q275G, C277Q, F278Y) with similar potency to that of wild-type c-Src; significantly more efficacious than multi-kinase inhibition in cell culture.
| M.Wt | 555.042 | |
| Formula | C32H23ClN8 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Brandvold KR, et al. ACS Chem Biol. 2012 Aug 17;7(8):1393-8.
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