KC01 |CAS:1646795-59-6 Probechem Biochemicals

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Chemical Structure : KC01

KC01 (ABHD16A inhibitor KC01)

Catalog No.: PC-62262Not For Human Use, Lab Use Only.

KC01 is a potent and selective inhibitor of ABHD16A with IC50 of 90 nM for hABHD16A, 520 nM for mABHD16A.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

KC01 is a potent and selective inhibitor of ABHD16A with IC50 of 90 nM for hABHD16A, 520 nM for mABHD16A.
KC01 shows significant reductions in all detected cellular lyso-PSs, no activity in other lipids, including PSs, PCs, PEs, lyso-PCs, lyso-PEs, or monoacylglycerols (MAGs).
KC01 decreases both lyso-PSs and lipopolysaccharide-induced cytokine production in mouse macrophages.

Physicochemical Properties

M.Wt	365.558
Formula	C22H39NO3
Appearance	Solid
CAS No.
Storage	Solide Powder -20 °C 12 Months; 4°C 6 Months	In Solvent -80 °C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	(Z)-6-(2-oxo-4-tridecyloxetan-3-ylidene)hexanamide

References

1. Kamat SS, et al. Nat Chem Biol. 2015 Feb;11(2):164-71.

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KC01 (ABHD16A inhibitor KC01)

Biological Activity

Physicochemical Properties

References

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