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KCI838PME

Chemical Structure : KCI838PME

CAS No.:

KCI838PME

Catalog No.: PC-27015Not For Human Use, Lab Use Only.

KCI838PME is a soluble 3’phosphate monoester prodrug of KCI838, AR-dependent growth by selectively binding to AR and blocking its association with ELK1, blocks AR binding to ELK1, inhibits enzalutamide-resistant patient-derived PCa tumor xenograft.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

KCI838PME is a soluble 3’phosphate monoester prodrug of KCI838, AR-dependent growth by selectively binding to AR and blocking its association with ELK1, blocks AR binding to ELK1, inhibits enzalutamide-resistant patient-derived PCa tumor xenograft.

Physicochemical Properties

M.Wt 459.22
Formula C17H11F3NNa2O6P
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

sodium 3-(5-hydroxy-4-oxo-1-(2,2,2-trifluoroethyl)-1,4-dihydroquinolin-2-yl)phenyl phosphate

References

1. Soave C, et al. bioRxiv [Preprint]. 2026 May 29:2026.05.26.727474.

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