KGDI-109 | PgDPP7 inhibitor | Probechem Biochemicals

Chemical Structure : KGDI-109

KGDI-109 (KGDI109)

Catalog No.: PC-26720Not For Human Use, Lab Use Only.

KGDI-109 is the first substrate-mimetic dipeptide inhibitor of P. gingivalis dipeptidyl peptidase 7 (PgDPP7) with IC50 of 53.8 uM and Ki of 25.1 uM, exerts an inhibitory effect against P. gingivalis growth with MIC of 1.56 uM.

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Biological Activity

Physicochemical Properties

M.Wt	465.93
Formula	C22H28ClN3O6
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	isopropyl (S)-2-((S)-2-amino-3-(4-nitrophenyl)propanamido)-3-(4-methoxyphenyl)propanoate hydrochloride

References

1. Patent JP2024008547 A 2024-01-19.

2. Aoki-Nonaka Y, et al. Sci Rep. 2026 May 8. doi: 10.1038/s41598-026-52648-8.

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KGDI-109 (KGDI109)

Biological Activity

Physicochemical Properties

References

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