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Chemical Structure : KGP-420
Catalog No.: PC-62812Not For Human Use, Lab Use Only.
KGP-420 is the water-soluble phosphate prodrug of KGP-94 in vivo studies, KGP-94 is a potent, selective cathepsin L inhibitor with IC50 of 189 nM.
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KGP-420 is the water-soluble phosphate prodrug of KGP-94 in vivo studies, KGP-94 is a potent, selective cathepsin L inhibitor with IC50 of 189 nM.
KGP-420 readily converts to KGP-94, and shows cytotoxicity against HUVECs with GI50 of 20.2 uM.
| M.Wt | 476.192 | |
| Formula | C14H13BrN3Na2O4PS | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Parker EN, et al. Bioorg Med Chem Lett. 2017 Mar 1;27(5):1304-1310.
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