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KIN1400

Chemical Structure : KIN1400

CAS No.: 446826-86-4

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KIN1400 (KIN-1400, KIN 1400)

Catalog No.: PC-70050Not For Human Use, Lab Use Only.

KIN1400 (KIN-1400) is a potent RIG-I-like receptor (RLR) agonist that triggers IRF3-dependent innate immune antiviral genes and IFN-β expression.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

    Biological Activity

    KIN1400 (KIN-1400) is a potent RIG-I-like receptor (RLR) agonist that triggers IRF3-dependent innate immune antiviral genes and IFN-β expression.
    KIN1400 shows antiviral activity against a broad range of RNA viruses, including dengue virus, and hepatitis C virus, as well as viruses of the families Filoviridae (Ebola virus), Orthomyxoviridae (influenza A virus), Arenaviridae (Lassa virus), and Paramyxoviridae (respiratory syncytial virus, Nipah virus).

    Physicochemical Properties

    M.Wt 449.476
    Formula C24H17F2N3O2S
    Appearance Solid
    CAS No.
    Storage
    Solide Powder
    -20 °C 12 Months; 4°C 6 Months
    In Solvent
    -80 °C 6 Months; -20°C 6 Months
    Shipping
    Solubility

    10 mM in DMSO
    Chemical Name/SMILES

    7-((benzo[d]thiazol-2-ylamino)(4-(difluoromethoxy)phenyl)methyl)quinolin-8-ol

    References

    1. Pattabhi S, et al. J Virol. 2015 Dec 16;90(5):2372-87.

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