Chemical Structure : KKL-10
CAS No.: 952849-76-2
Catalog No.: PC-61265Not For Human Use, Lab Use Only.
KKL-10 is a small-molecule inhibitor of bacterial ribosome rescue that exhibits broad-spectrum antimicrobial activity against bacteria grown in liquid culture.
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KKL-10 is a small-molecule inhibitor of bacterial ribosome rescue that exhibits broad-spectrum antimicrobial activity against bacteria grown in liquid culture; exhibits exceptional antimicrobial activity against both attenuated (LVS) and fully virulent strains of F. tularensis (Schu S4) in vitro with MIC of 0.12 and 0.48 ug/mL, respectively; arrests intracellular growth of F. tularensis during all stages of infection, does not affect macrophage viability or function.
M.Wt | 364.217 | |
Formula | 4H10BrN3O2S | |
Appearance | Solid | |
Storage |
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Solubility |
10 mM in DMSO |
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Chemical Name/SMILES |
5-Bromo-N-[5-(4-methylphenyl)-1,3,4-oxadiazol-2-yl]-2-thiophenecarboxamide |
1. Goralski TD, et al. Antimicrob Agents Chemother. 2016 May 23;60(6):3276-82.
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