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Chemical Structure : KKL-35
CAS No.: 865285-29-6
Catalog No.: PC-70354Not For Human Use, Lab Use Only.
KKL-35 is a small molecule inhibitor of trans-translation that has broad-spectrum antibiotic activity, inhibits the trans-translation tagging reaction with an IC50 of 0.9 uM.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 5 mg | $98 | In stock | |
| 10 mg | $148 | In stock | |
| 25 mg | $258 | In stock | |
| 50 mg | $428 | In stock | |
| 100 mg | Get quote |
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KKL-35 is a small molecule inhibitor of trans-translation that has broad-spectrum antibiotic activity, inhibits the trans-translation tagging reaction with an IC50 of 0.9 uM.
KKL-35 exhibits broad-spectrum antibiotic activity, validating trans-translation as a target for drug development.
KKL-35 prevented growth of B. anthracis and M. smegmatis with MIC values ≤6 µM (<2 µg/mL).
| M.Wt | 317.7 | |
| Formula | C15H9ClFN3O2 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
|
| Chemical Name/SMILES |
3-chloro-N-(1-propyl-1H-tetrazol-5-yl)benzamide |
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1. Ramadoss NS, et al. Proc Natl Acad Sci U S A. 2013 Jun 18;110(25):10282-7.
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