Catalog No.: PC-61266Not For Human Use, Lab Use Only.
KKL-40 is a small-molecule inhibitor of bacterial ribosome rescue that exhibits broad-spectrum antimicrobial activity against bacteria grown in liquid culture.
KKL-40 is a small-molecule inhibitor of bacterial ribosome rescue that exhibits broad-spectrum antimicrobial activity against bacteria grown in liquid culture.
KKL-40 exhibited exceptional antimicrobial activity against both attenuated (LVS) and fully virulent strains of F. tularensis (Schu S4) in vitro with MIC of 0.12 and 0.44 ug/mL, respectively.
KKL-40 arrests intracellular growth of F. tularensis during all stages of infection, does not affect macrophage viability or function.
