KLHDC2-BRD4 PROTAC K2-B4-5e

You are here:Home-ADCs and PROTACs-PROTAC-KLHDC2-BRD4 PROTAC K2-B4-5e

Chemical Structure : KLHDC2-BRD4 PROTAC K2-B4-5e

Catalog No.: PC-22819Not For Human Use, Lab Use Only.

KLHDC2-BRD4 PROTAC K2-B4-5e is a hihgly potent KLHDC2-directed PROTAC degrader of BRD4 with DC50 of 6.2 nM against HiBiT-BRD4, Dmax=93%, in PC-3 cells.

Packing	Price	Stock	Quantity
50 mg		Get quote
100 mg		Get quote
250 mg		Get quote

Get Quotation Now

* Please select Quantity before adding items.

or Bulk Inquiry

Bulk size, bulk discount!

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

Purity & Documentation Purity: >98% (HPLC)

Biological Activity

KLHDC2-BRD4 PROTAC K2-B4-5e is a hihgly potent KLHDC2-directed PROTAC degrader of BRD4 with DC50 of 6.2 nM against HiBiT-BRD4, Dmax=93%, in PC-3 cells.

Physicochemical Properties

M.Wt	949.52
Formula	C52H49ClN8O6S
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	methyl (S)-2-(5-(7-(4'-(2-(4-(4-chlorophenyl)-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepin-6-yl)acetamido)-[1,1'-biphenyl]-4-carbonyl)-3-isobutyl-2-oxo-5,6,7,8-tetrahydro-1,7-naphthyridin-1(2H)-yl)-2-oxopyridin-1(2H)-yl)acetate

References

1. Hickey CM, et al. Nat Struct Mol Biol. 2024 Feb;31(2):311-322.

Overnight Delivery
Fast & Safe Delivery Worldwide
Rewards Program

About Us

Our Services

Site Map

Join with Us
Product Use Citations

Pharmacological Glossary Abbreviations

Abbreviations

Quality Manual

Inquiry Form
How to Order

Terms & Conditions

Credit Card Payment

Shipping Rates & Policies

Privacy Policy
sales@probechem.com

Select Your Country or Region