Welcome to ProbeChem!Global Supplier of Chemical Probes, Inhibitors & Agonists.

You are here:Home-Chemical Inhibitors & Agonists-Metabolic Enzyme/Protease-Monoacylglycerol Lipase (MAGL)-KML29
KML29

Chemical Structure : KML29

CAS No.: 1380424-42-9

KML29 (KML-29)

Catalog No.: PC-45584Not For Human Use, Lab Use Only.

KML29 is a potent, highly selective MAGL (monoacylglycerol lipase) inhibitor with IC50 of 15 nM.

Packing Price Stock Quantity
5 mg $48 In stock
10 mg $78 In stock
25 mg $128 In stock
50 mg $218 In stock
100 mg Get quote

Bulk size, bulk discount!

Welcome credit card payment!

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

KML29 is a potent, highly selective MAGL (monoacylglycerol lipase) inhibitor with IC50 of 15 nM.
KML29 shows no cross-activity with FAAH or other serine hydrolases.
KML29 potently inhibits 2-AG hydrolysis, but does not affect AEA hydrolysis.
KML29 reduces inflammatory and neuropathic nociceptive behaviour without occurrence of cannabimimetic side effects.

Physicochemical Properties

M.Wt 549.4164
Formula C24H21F6NO7
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

1-Piperidinecarboxylic acid, 4-[bis(1,3-benzodioxol-5-yl)hydroxymethyl]-, 2,2,2-trifluoro-1-(trifluoromethyl)ethyl ester

References

1. Ignatowska-Jankowska BM, et al. Br J Pharmacol. 2014 Mar;171(6):1392-407.

2. Pasquarelli N, et al. Neuropharmacology. 2015 Apr;91:148-56.

3. Chang JW, et al. Chem Biol. 2012 May 25;19(5):579-88.

Copyright © 2022 probechem.com. All Rights Reserved. probechem Copyright

Contact Us sales@probechem.com

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

  • *Product name:
  • *Applicant name:
  • *Email address:
  • *Organization name:
  • *Requested quantity:
  • *Country:
  • *Additional Information:

Get Quote

* Indicates a Required FieldYour information is safe with us.

  • *Product name:
  • *Applicant name:
  • *Email address:
  • *Organization name:
  • *Requested quantity:
  • *Country:
  • Additional Information: