KNa1.1 blocker Z05 | KNa1.1 (Slack) inhibitor

Chemical Structure : KNa1.1 blocker Z05

KNa1.1 blocker Z05 (Compound Z05)

Catalog No.: PC-23273Not For Human Use, Lab Use Only.

KNa1.1 blocker Z05 is a selective potential KNa1.1 (Slack, Slo2.2, or KCa4.1) inhibitor with IC50 of 3.4 uM and 0.2 uM for WT KNa1.1 and mutant Y796H respectively.

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Biological Activity

KNa1.1 blocker Z05 is a selective potential KNa1.1 (Slack, Slo2.2, or KCa4.1) inhibitor with IC50 of 3.4 uM and 0.2 uM for WT KNa1.1 and mutant Y796H respectively.

Physicochemical Properties

M.Wt	345.49
Formula	C24H27NO
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	4-(2-(2-(Benzyloxy)naphthalen-1-yl)ethyl)piperidine

References

1. Zheng R, et al. J Med Chem. 2024 Oct 24. doi: 10.1021/acs.jmedchem.4c01815.

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KNa1.1 blocker Z05 (Compound Z05)

Biological Activity

Physicochemical Properties

References

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