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KNa1.1 blocker Z05

Chemical Structure : KNa1.1 blocker Z05

CAS No.: 3037315-44-6

KNa1.1 blocker Z05 (Compound Z05)

Catalog No.: PC-23273Not For Human Use, Lab Use Only.

KNa1.1 blocker Z05 is a selective potential KNa1.1 (Slack, Slo2.2, or KCa4.1) inhibitor with IC50 of 3.4 uM and 0.2 uM for WT KNa1.1 and mutant Y796H respectively.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

KNa1.1 blocker Z05 is a selective potential KNa1.1 (Slack, Slo2.2, or KCa4.1) inhibitor with IC50 of 3.4 uM and 0.2 uM for WT KNa1.1 and mutant Y796H respectively.

Physicochemical Properties

M.Wt 345.49
Formula C24H27NO
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

4-(2-(2-(Benzyloxy)naphthalen-1-yl)ethyl)piperidine

References

1. Zheng R, et al. J Med Chem. 2024 Oct 24. doi: 10.1021/acs.jmedchem.4c01815.

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