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Chemical Structure : KR-32570
Catalog No.: PC-35054Not For Human Use, Lab Use Only.
KR-32570 is a potent sodium hydrogen exchanger NHE1 inhibitor with IC50 of 50 nM.
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KR-32570 is a potent sodium hydrogen exchanger NHE1 inhibitor with IC50 of 50 nM.
KR-32570 significantly and concentration dependently improves cardiac contractile function and severe contracture in conjunction with causing a marked reduction in lactate dehydrogenase release at 1-10 uM.
KR-32570 possesses potent cardioprotective effects in perfused rat hearts.
| M.Wt | 293.707 | |
| Formula | C13H12ClN3O3 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Lee BH, et al. Eur J Pharmacol. 2005 Mar 28;511(2-3):175-82.
2. Lee S, et al. J Med Chem. 2005 Apr 21;48(8):2882-91.
3. Kim MJ, et al. Eur J Pharmacol. 2005 Nov 21;525(1-3):1-7.
4. Lee KS, et al. Arch Pharm Res. 2006 May;29(5):375-83.
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