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KR-33494

Chemical Structure : KR-33494

CAS No.: 1021497-97-1

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KR-33494 (KM-819, KR33494)

Catalog No.: PC-62703Not For Human Use, Lab Use Only.

KM-819 (KR-33493) is a potent small molecule inhibitor of FAF1 (FAS-associated factor 1), inhibits Fas-mediated cell death.

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10 mg $128 In stock
25 mg $218 In stock
50 mg $378 In stock
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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

KM-819 (KR-33493) is a potent small molecule inhibitor of FAF1 (FAS-associated factor 1), inhibits Fas-mediated cell death.
KM-819 (KR-33493) has shown potential for preventing dopaminergic neuronal cell death, promoting the degradation of α-synuclein and preventing its accumulation.

Physicochemical Properties

M.Wt 460.346
Formula C20H18BrN3O3S
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

4-[[2-[(4-bromophenyl)thio]acetyl]amino]-1-(2-phenylethyl)-1H-pyrazole-3-carboxylic acid

References

1. Yoo SE, et al. Bioorg Med Chem Lett. 2016 Feb 15;26(4):1169-72.

2. Suh J, et al. Bioorg Med Chem Lett. 2010 Nov 15;20(22):6362-5.

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