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KRev-202

Chemical Structure : KRev-202

CAS No.: 3059122-53-8

KRev-202 (KRev202)

Catalog No.: PC-27740Not For Human Use, Lab Use Only.

KRev-202 is a water-soluble prodrug (49 mg/mL) of the potent and selective JNK inhibitor Tanzisertib (CC-930, CC930), prevent ischemia-induced acute kidney injury (AKI).

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

KRev-202 is a water-soluble prodrug (49 mg/mL) of the potent and selective JNK inhibitor Tanzisertib (CC-930, CC930), prevent ischemia-induced acute kidney injury (AKI).

Physicochemical Properties

M.Wt 574.40
Formula C21H24F3N6O5P.2Na
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

(1S,4r)-4-((9-((S)-tetrahydrofuran-3-yl)-8-((2,4,6-trifluorophenyl)amino)-9H-purin-2-yl)amino)cyclohexyl dihydrogen phosphate, sodium salt

References

1. Nikolic-Paterson DJ, et al. Front Pharmacol. 2026 Jan 30;16:1667221.

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