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Chemical Structure : KS-99
Catalog No.: PC-70205Not For Human Use, Lab Use Only.
KS-99 (KS99) is a novel dual inhibitor of BTK and tubulin polymerization.
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KS-99 (KS99) is a novel dual inhibitor of BTK and tubulin polymerization; interacts directly with the catalytic domain of BTK and inhibits phosphorylation at the Y223 residue and kinase activities; reduces the cell viability of MM and CD138+ cells (IC50=0.5-1 uM); inhibits the in vivo tumor growth of MM cells through the inhibition of BTK and tubulin.
| M.Wt | 466.147 | |
| Formula | C17H10Br2N2O2S | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Pandey MK, et al. Exp Hematol. 2017 Jun 22. pii: S0301-472X(17)30233-3.
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