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KSK67

Chemical Structure : KSK67

CAS No.: 1638100-60-3

KSK67 (KSK 67)

Catalog No.: PC-38713Not For Human Use, Lab Use Only.

KSK67 is a potent small molecule inhibitor of bacterial transcriptional activator PrfA with IC50 of 67 nM, reduces virulence factor expression in L. monocytogene.

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    Biological Activity

    KSK67 is a potent small molecule inhibitor of bacterial transcriptional activator PrfA with IC50 of 67 nM, reduces virulence factor expression in L. monocytogene.

    Physicochemical Properties

    M.Wt 391.485
    Formula C23H21NO3S
    Appearance Solid
    CAS No.
    Storage
    Solide Powder
    -20°C 12 Months; 4°C 6 Months
    In Solvent
    -80°C 6 Months; -20°C 6 Months
    Shipping
    Solubility

    10 mM in DMSO

    Chemical Name/SMILES

    (R)-8-cyclopropyl-7-((4-methylnaphthalen-1-yl)methyl)-5-oxo-2,3-dihydro-5H-thiazolo[3,2-a]pyridine-3-carboxylic acid

    References

    1. Thao Thanh Tran, et al. PLoS Pathog. 2022 Jan 10;18(1):e1010166.

    2. James A D Good, et al. Cell Chem Biol. 2016 Mar 17;23(3):404-14.

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