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Chemical Structure : KT-5823
CAS No.: 126643-37-6
Catalog No.: PC-63045Not For Human Use, Lab Use Only.
KT-5823 is a potent, highly specific PKG (cGMP-dependent protein kinase) inhibitor with Ki of 0.234 uM.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 100 ug | $248 | In stock | |
| 500 ug | $598 | In stock | |
| 1 mg | Get quote |
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KT-5823 is a potent, highly specific PKG (cGMP-dependent protein kinase) inhibitor with Ki of 0.234 uM.
KT-5823 also inhibits PKA and PKC with Ki values of 10 μM and 4 μM, respectively.
KT-5823 arresst cells at a later time that is approximately 6 h after the G0/G1 boundary.
| M.Wt | 495.525 | |
| Formula | C29H25N3O5 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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| Chemical Name/SMILES |
9,12-Epoxy-1H-diindolo[1,2,3-fg:3',2',1'-kl]pyrrolo[3,4-i][1,6]benzodiazocine-10-carboxylic acid, 2,3,9,10,11,12-hexahydro-10-methoxy-2,9-dimethyl-1-oxo-, methyl ester, [9S-(9α,10β,12α)]- |
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1. Gadbois DM, et al. Proc Natl Acad Sci U S A. 1992 Sep 15;89(18):8626-30.
2. Burkhardt M, et al. J Biol Chem. 2000 Oct 27;275(43):33536-41.
3. Beyer S, et al. Endocrinology. 2011 Mar;152(3):782-92.
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