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Chemical Structure : KT-5823
Catalog No.: PC-63045Not For Human Use, Lab Use Only.
KT-5823 is a potent, highly specific PKG (cGMP-dependent protein kinase) inhibitor with Ki of 0.234 uM, displays little to no activity for MLCK, cAPK, and PKC.
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KT-5823 is a potent, highly specific PKG (cGMP-dependent protein kinase) inhibitor with Ki of 0.234 uM, displays little to no activity for MLCK, cAPK, and PKC.
KT-5823 arresst cells at a later time that is approximately 6 h after the G0/G1 boundary.
| M.Wt | 495.525 | |
| Formula | C29H25N3O5 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Gadbois DM, et al. Proc Natl Acad Sci U S A. 1992 Sep 15;89(18):8626-30.
2. Burkhardt M, et al. J Biol Chem. 2000 Oct 27;275(43):33536-41.
3. Beyer S, et al. Endocrinology. 2011 Mar;152(3):782-92.
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