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KT182

Chemical Structure : KT182

CAS No.: 1402612-62-7

KT182 (KT-182)

Catalog No.: PC-20130Not For Human Use, Lab Use Only.

KT-182 (KT182) is a potent, selective, irreversible α/β-hydrolase domain 6 (ABHD6) inhibitor with IC50 of 1.7 nM.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

KT-182 (KT182) is a potent, selective, irreversible α/β-hydrolase domain 6 (ABHD6) inhibitor with IC50 of 1.7 nM.
KT182 exhibits selectively for ABHD6 over other brain and liver serine hydrolases.
KT182 (1 mg/kg, i.p.) inhibits ABHD6 in liver and brain extracts in mice.

Physicochemical Properties

M.Wt 438.53
Formula C27H26N4O2
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

(4-(3'-(hydroxymethyl)-[1,1'-biphenyl]-4-yl)-1H-1,2,3-triazol-1-yl)(2-phenylpiperidin-1-yl)methanone

References

1. Ku-Lung Hsu, et al. J Med Chem. 2013 Nov 14;56(21):8270-9.

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