Chemical Structure : KT182
CAS No.: 1402612-62-7
Catalog No.: PC-20130Not For Human Use, Lab Use Only.
KT-182 (KT182) is a potent, selective, irreversible α/β-hydrolase domain 6 (ABHD6) inhibitor with IC50 of 1.7 nM.
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KT-182 (KT182) is a potent, selective, irreversible α/β-hydrolase domain 6 (ABHD6) inhibitor with IC50 of 1.7 nM.
KT182 exhibits selectively for ABHD6 over other brain and liver serine hydrolases.
KT182 (1 mg/kg, i.p.) inhibits ABHD6 in liver and brain extracts in mice.
M.Wt | 438.53 | |
Formula | C27H26N4O2 | |
Appearance | Solid | |
Storage |
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Solubility |
10 mM in DMSO |
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Chemical Name/SMILES |
(4-(3'-(hydroxymethyl)-[1,1'-biphenyl]-4-yl)-1H-1,2,3-triazol-1-yl)(2-phenylpiperidin-1-yl)methanone |
1. Ku-Lung Hsu, et al. J Med Chem. 2013 Nov 14;56(21):8270-9.
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