Catalog No.: PC-26139Not For Human Use, Lab Use Only.
KTX-951 is a potent and orally active degrader of IRAK4 and the Ikaros and Aiolos (IMiD) substrates with DC50 of 13 nM, 14 nM and 13 nM for IRAK4, Ikaros and Aiolos, respectively, induces proteasomal degradation of these key proteins, leading to the dual inhibition of the NF-κB and IRF4 signaling pathways.
KTX-951 is a potent and orally active degrader of IRAK4 and the Ikaros and Aiolos (IMiD) substrates with DC50 of 13 nM, 14 nM and 13 nM for IRAK4, Ikaros and Aiolos, respectively, induces proteasomal degradation of these key proteins, leading to the dual inhibition of the NF-κB and IRF4 signaling pathways.
