KW-2581 |CAS:284045-56-3 Probechem Biochemicals

You are here:Home-Chemical Inhibitors & Agonists-Metabolic Enzyme/Protease-Steroid Sulfatase (STS)-KW-2581

Chemical Structure : KW-2581

KW-2581 (KW2581)

Catalog No.: PC-61434Not For Human Use, Lab Use Only.

A novel potent, irreversible and orally active inhibitor of steroid sulfatase (STS) with IC50 of 13 nM in ZR-75-1 cells.

Packing	Price	Stock	Quantity
100 mg		Get quote
250 mg		Get quote
500 mg		Get quote
1 g		Get quote

Get Quotation Now

* Please select Quantity before adding items.

or Bulk Inquiry

Bulk size, bulk discount!

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

Purity & Documentation Purity: >98% (HPLC)

Biological Activity

A novel potent, irreversible and orally active inhibitor of steroid sulfatase (STS) with IC50 of 13 nM in ZR-75-1 cells; inhibits the E1S-stimulated growth of ZR-75-1 cells, reduces the expression of E1S-induced progesterone receptors at concentrations as low as 0.1 nM; causes tumor shrinkage in a mouse xenograft model.

Breast Cancer

Discontinued

Physicochemical Properties

M.Wt	460.633
Formula	C25H36N2O4S
Appearance	Solid
CAS No.
Storage	Solide Powder -20 °C 12 Months; 4°C 6 Months	In Solvent -80 °C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	[(8S,9S,13S,14S)-17-[di(propan-2-yl)carbamoyl]-13-methyl-6,7,8,9,11,12,14,15-octahydrocyclopenta[a]phenanthren-3-yl] sulfamate

References

1. Ishida H, et al. Breast Cancer Res Treat. 2007 Aug;104(2):211-9.

2. Ishida H, et al. Breast Cancer Res Treat. 2007 Dec;106(2):215-27

3. Ishida H, et al. J Steroid Biochem Mol Biol. 2008 Jan;108(1-2):17-22.

Overnight Delivery
Fast & Safe Delivery Worldwide
Rewards Program

About Us

Our Services

Site Map

Join with Us
Product Use Citations

Pharmacological Glossary Abbreviations

Abbreviations

Quality Manual

Inquiry Form
How to Order

Terms & Conditions

Credit Card Payment

Shipping Rates & Policies

Privacy Policy
sales@probechem.com

KW-2581 (KW2581)

Biological Activity

Physicochemical Properties

References

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

Get Quote

* Indicates a Required FieldYour information is safe with us.