Welcome to Shanghai Probechem Biochemicals Co Ltd !Global Supplier of Chemical Probes, Inhibitors & Agonists.
Chemical Structure : KY-02061
Catalog No.: PC-63513Not For Human Use, Lab Use Only.
KY-02061 is a small-molecule inhibitor of Dishevelled-CXXC5 interaction with IC50 of 24 uM in vitro binding assay.
Bulk size, bulk discount!
E-mail: sales@probechem.com
Tech Support: tech@probechem.com
KY-02061 is a small-molecule inhibitor of Dishevelled-CXXC5 interaction with IC50 of 24 uM in vitro binding assay.
KY-02061 increases the activation of the Wnt/β-catenin pathway in a dose-dependent manner as revealed by the TOPflash reporter assay.
ALP activity also increased in a dose‐dependent manner in KY-02061-treated primary osteoblast cells.
KY-02061 increases levels of Runx2, an osteoblast differentiation marker, and β-catenin
| M.Wt | 445.486 | |
| Formula | C22H23NO7S | |
| Appearance | Solid | |
| Storage |
|
|
| Solubility |
10 mM in DMSO |
|
1. Kim HY, et al. EMBO Mol Med. 2016 Apr 1;8(4):375-87.
Copyright © 2022 probechem.com. All Rights Reserved. probechem Copyright
