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KY02111

Chemical Structure : KY02111

CAS No.: 1118807-13-8

KY02111 (KY 02111)

Catalog No.: PC-21485Not For Human Use, Lab Use Only.

KY02111 is a small molecule canonical WNT signaling inhibitor, promotes differentiation of hPSCs to cardiomyocytes.

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Biological Activity

KY02111 is a small molecule canonical WNT signaling inhibitor, promotes differentiation of hPSCs to cardiomyocytes.
KY02111 acts downstream of APC and GSK3β to inhibit WNT signaling.
KY02111 and WNT inhibitors cooperatively enhance hPSC cardiomyogenesis.
KY02111and WNT modulators permit cytokine and xeno-free hPSC cardiomyogenesis.

Physicochemical Properties

M.Wt 376.86
Formula C18H17ClN2O3S
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

N-(6-Chlorobenzo[d]thiazol-2-yl)-3-(3,4-dimethoxyphenyl)propanamide

References

1. Minami I, et al. Cell Rep. 2012 Nov 29;2(5):1448-60.

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