Chemical Structure : KYT-1
Catalog No.: PC-72420Not For Human Use, Lab Use Only.
KYT-1 is a potent, selective inhibitor of P. gingivalis virulence factor Arg-gingipain (Rgp) with Ki 40 nM (RgpA/B).
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KYT-1 is a potent, selective inhibitor of P. gingivalis virulence factor Arg-gingipain (Rgp) with Ki 40 nM (RgpA/B).
KYT-1 showed significant inhibitory effects on SMC proliferation stimulated by Porphyromonas gingivalis.
M.Wt | 619.768 | |
Formula | C29H49N9O6 | |
Appearance | Solid | |
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1. Kadowaki T, et al. Mol Pharmacol. 2004 Dec;66(6):1599-606.
2. Hosn KN, et al. Clin Exp Dent Res. 2015 Oct 27;1(1):18-25.
3. Inaba H, et al. J Periodontol. 2011 Nov;82(11):1616-22.
4. Cao C, et al. Int J Clin Exp Med. 2015 Oct 15;8(10):18327-34.
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