Chemical Structure : Kalamycin
CAS No.:
11048-15-0
Kalamycin
(Kalafungin, U-19718, NSC137443)
Catalog No.: PC-27208Not For Human Use, Lab Use Only.
Kalamycin (Kalafungin, U-19718, NSC137443) is an antibiotic, antimicrobial agent and β-lactamase inhibitor from marine Streptomyces, also is a potent inhibitor of METTL1 methyltransferase activity with IC50 of 8.9 uM, demonstrates potent antileukemia efficacy, also shows inhibitory activities against a variety of pathogenic fungi, yeasts, protozoa, gram-positive bacteria.
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Purity & Documentation Purity:
>98% (HPLC)
Biological Activity
Kalamycin (Kalafungin, U-19718, NSC137443) is an antibiotic, antimicrobial agent and β-lactamase inhibitor from marine Streptomyces, also is a potent inhibitor of METTL1 methyltransferase activity with IC50 of 8.9 uM, demonstrates potent antileukemia efficacy, also shows inhibitory activities against a variety of pathogenic fungi, yeasts, protozoa, gram-positive bacteria.
Physicochemical Properties
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M.Wt
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302.24
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Formula
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C15H10O7
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Appearance
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Solid
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CAS No.
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Storage
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- Solide Powder
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-20°C 12 Months; 4°C 6 Months
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- In Solvent
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-80°C 6 Months; -20°C 6 Months
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Shipping
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Solubility
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10 mM in DMSO
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Chemical Name/SMILES
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(3aS,5S,11bS)-7-Hydroxy-5-methyl-3aH-benzo[g][1,3]dioxolo[4,5-c]isochromene-2,6,11(5H,11bH)-trione
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References
1. Johnson LE, et al. 1968 Dec;16(12):1815-21.
2. Ren L, et al. Blood. 2026 Jun 18;147(25):3069-3085.
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