Kv7 activator compound 60

Chemical Structure : Kv7 activator compound 60

Catalog No.: PC-27786Not For Human Use, Lab Use Only.

Kv7 activator compound 60 is a potent and photochemically stable neuronal Kv7 channel activator with EC50 of 0.1 uM for Kv7.2/Kv7.3 channels.

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Biological Activity

Kv7 activator compound 60 is a potent and photochemically stable neuronal Kv7 channel activator with EC50 of 0.1 uM for Kv7.2/Kv7.3 channels.

M.Wt	397.42
Formula	C20H23F4N3O
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	N-(2-amino-3-fluoro-4-((4-(trifluoromethyl)benzyl)amino)phenyl)-3,3-dimethylbutanamide

1. Ciaglia T, et al. Angew Chem Int Ed Engl. 2026 Aug 22:e7948330.

2. Simona Musella, et al. J Med Chem. 2022 Aug 25;65(16):11340-11364.