Chemical Structure : L-368,899 hydrochloride
CAS No.:
160312-62-9
L-368,899 hydrochloride
Catalog No. : PC-24224Not For Human Use, Lab Use Only.
L-368,899 hydrochloride is a potent, selective orally bioavailable, non-peptide oxytocin receptor (OTR, OXTR) antagonist with IC50 of 8.9 nM (rat uterus), and 26 nM (human uterus).
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Purity & Documentation Purity:
>98% (HPLC) Select Batch: PC-2422401
Biological Activity
L-368,899 hydrochloride is a potent, selective orally bioavailable, non-peptide oxytocin receptor (OTR, OXTR) antagonist with IC50 of 8.9 nM (rat uterus), and 26 nM (human uterus).
Physicochemical Properties
M.Wt
591.22
Formula
C26H43ClN4O5S2
Appearance
Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility
10 mM in DMSO
Chemical Name/SMILES
(2S)-2-amino-N-((1S,2S)-7,7-dimethyl-1-(((4-(o-tolyl)piperazin-1-yl)sulfonyl)methyl)bicyclo[2.2.1]heptan-2-yl)-4-(methylsulfonyl)butanamide hydrochloride
References
1. Williams PD, et al. J Med Chem. 1994 Mar 4;37(5):565-71.
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