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L-573655

Chemical Structure : L-573655

CAS No.: 112507-21-8

L-573655 (L-573, 655)

Catalog No.: PC-24470Not For Human Use, Lab Use Only.

L-573655 (L-573,655) is a specific small molecule inhibitor of UDP-3-O-(R-3-hydroxymyristoyl)-N-acetylglucosamine deacetylase (LpxC), inhibits E. coli LpxC with Ki values of 24 uM and approximately 50 nM, respectively.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

L-573655 (L-573,655) is a specific small molecule inhibitor of UDP-3-O-(R-3-hydroxymyristoyl)-N-acetylglucosamine deacetylase (LpxC), inhibits E. coli LpxC with Ki values of 24 uM and approximately 50 nM, respectively.

Physicochemical Properties

M.Wt 206.20
Formula C10H10N2O3
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

N-Hydroxy-2-phenyl-4,5-dihydrooxazole-4-carboxamide

References

1. Jackman JE, et al. J Biol Chem. 2000 Apr 14;275(15):11002-9.

2. Onishi HR, et al. Science. 1996 Nov 8;274(5289):980-2.

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