Welcome to Shanghai Probechem Biochemicals Co Ltd !Global Supplier of Chemical Probes, Inhibitors & Agonists.
Chemical Structure : L-685458
CAS No.: 292632-98-5
Catalog No.: PC-45626Not For Human Use, Lab Use Only.
A potent inhibitor of amyloid β-protein precursor gamma-secretase activity (IC50=14 nM).
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 5 mg | $352 | In stock | |
| 10 mg | $672 | In stock |
Bulk size, bulk discount!
E-mail: sales@probechem.com
Tech Support: tech@probechem.com
A potent inhibitor of amyloid β-protein precursor gamma-secretase activity (IC50=14 nM); shows similar potency for inhibition of A beta(42) and A beta(40) peptides.
| M.Wt | 672.8534 | |
| Formula | C39H52N4O6 | |
| Appearance | Solid | |
| Storage |
|
|
| Solubility |
DMSO: ≥ 31 mg/mL |
|
| Chemical Name/SMILES |
L-Phenylalaninamide, N-[(2R,4R,5S)-5-[[(1,1-dimethylethoxy)carbonyl]amino]-4-hydroxy-1-oxo-6-phenyl-2-(phenylmethyl)hexyl]-L-leucyl- |
|
1. Shearman MS, et al. Biochemistry. 2000 Aug 1;39(30):8698-704.
2. Pozdnyakov N, et al. J Biol Chem. 2013 Apr 5;288(14):9710-20.
3. Liu F, et al. Eur J Neurosci. 2013 May;37(10):1714-25.
Copyright © 2022 probechem.com. All Rights Reserved. probechem Copyright
