Chemical Structure : L-701324
CAS No.: 142326-59-8
Catalog No.: PC-45532Not For Human Use, Lab Use Only.
A potent, orally active antagonist at the glycine modulatory site on NMDA receptor with IC50 of 2 nM.
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50 mg | $280 | In stock |
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A potent, orally active antagonist at the glycine modulatory site on NMDA receptor with IC50 of 2 nM; is a potent, p.o. active anticonvulsant with a reduced propensity to activate mesolimbic dopaminergic systems in rodents.
Anxiety
Discontinued
M.Wt | 363.7938 | |
Formula | C21H14ClNO3 | |
Appearance | Solid | |
Storage |
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Solubility |
DMSO: ≥ 34 mg/mL |
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Chemical Name/SMILES |
2(1H)-Quinolinone, 7-chloro-4-hydroxy-3-(3-phenoxyphenyl)- |
1. Kulagowski JJ, et al. J Med Chem. 1994 May 13;37(10):1402-5.
2. Bristow LJ, et al. J Pharmacol Exp Ther. 1996 Nov;279(2):492-501.
3. Hutson PH, et al. Eur J Pharmacol. 1997 May 20;326(2-3):127-32.
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