L-902688 | EP4 agonist | Probechem Biochemicals

Chemical Structure : L-902688

L-902688 (L-902,688, L902688)

Catalog No.: PC-22027Not For Human Use, Lab Use Only.

L-902688 (L-902,688) is a potent, selective and orally active EP4 receptor agonist with Ki of 0.38 nM and EC50 of 0.6 nM, >4,000-fold selective for EP4 over other EP and prostanoid receptors.

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Biological Activity

L-902688 (L-902,688) is a potent, selective and orally active EP4 receptor agonist with Ki of 0.38 nM and EC50 of 0.6 nM, >4,000-fold selective for EP4 over other EP and prostanoid receptors.

Physicochemical Properties

M.Wt	419.48
Formula	C21H27F2N5O2
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	(5R)-5-[(1E,3R)-4,4-Difluoro-3-hydroxy-4-phenyl-1-buten-1-yl]-1-[6-(2H-tetrazol-5-yl)hexyl]-2-pyrrolidinone

References

1. Young, R.N., et al. Heterocycles. 2004, 64, 437-445.

2. Lai YJ, et al. Int J Mol Sci. 2018 Mar 3;19(3). pii: E727.

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L-902688 (L-902,688, L902688)

Biological Activity

Physicochemical Properties

References

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