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L-BHDU

Chemical Structure : L-BHDU

CAS No.: 161105-93-7

L-BHDU

Catalog No.: PC-22614Not For Human Use, Lab Use Only.

L-BHDU is a potent and selective inhibitor of the varicella-zoster virus (VZV) with EC50 of 0.25 uM in human foreskin fibroblasts (HFFs).

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

L-BHDU is a potent and selective inhibitor of the varicella-zoster virus (VZV) with EC50 of 0.25 uM in human foreskin fibroblasts (HFFs).

Physicochemical Properties

M.Wt 319.11
Formula C10H11BrN2O5
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

5-((E)-2-Bromovinyl)-1-((2S,4S)-2-(hydroxymethyl)-1,3-dioxolan-4-yl)pyrimidine-2,4(1H,3H)-dione

References

1. De C, et al. Antiviral Res. 2014 Oct;110:10-9.

2. Singh US, et al. J Med Chem. 2023 May 25;66(10):7038-7053.

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