Catalog No.: PC-63316Not For Human Use, Lab Use Only.
LAF389 is a potent methionine aminopeptidase (MetAP) inhibitor with IC50 of 800 nM for MetAP-2, inhibits both MetAP1 and 2, potently inhibits HUVEC proliferation with IC50 of 20 nM.
LAF389 is a potent methionine aminopeptidase (MetAP) inhibitor with IC50 of 800 nM for MetAP-2, inhibits both MetAP1 and 2, potently inhibits HUVEC proliferation with IC50 of 20 nM.
LAF389 demonstrates both antiproliferative and antiangiogenetic properties, and preclinical investigations showed a broad antitumour activity.
