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LAS-131

Chemical Structure : LAS-131

CAS No.: 2178095-22-0

LAS-131 (LAS131)

Catalog No.: PC-26488Not For Human Use, Lab Use Only.

LAS-131 is a specific small molecule inhibitor of HSV-1 terminase complex (pUL15), selectively inhibits the reproduction of acyclovir-sensitive and -resistant HSV-1 variants with IC50 of 1.95 ug/mL

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

LAS-131 is a specific small molecule inhibitor of HSV-1 terminase complex (pUL15), selectively inhibits the reproduction of acyclovir-sensitive and -resistant HSV-1 variants with IC50 of 1.95 ug/mL

Physicochemical Properties

M.Wt 416.43
Formula C20H22F2N6O2
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

(3S)-4-[6-(purin-6-yl)aminohexanoyl]-3,4-dihydro-3-methyl-7,8-difluoro-2H-[1,4]-benzoxazine

References

1. Galegov GA, et al. Vopr Virusol. 2026 Feb 28;71(1):21-31.

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