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LASSBio-2337

Chemical Structure : LASSBio-2337

CAS No.:

LASSBio-2337

Catalog No.: PC-26400Not For Human Use, Lab Use Only.

LASSBio-2337 is a potent, dual pan-PI3K/mTOR inhibitor with IC50 of 0.3, 4.2, 0.6, 7.5 and 5.8 uM for PI3Kα, PI3Kβ, PI3Kδ, PI3Kγ and mTOR respectively, shows cytotoxic effects in leukemia cell lines with CC50 of 4.37-9.44 uM.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

LASSBio-2337 is a potent, dual pan-PI3K/mTOR inhibitor with IC50 of 0.3, 4.2, 0.6, 7.5 and 5.8 uM for PI3Kα, PI3Kβ, PI3Kδ, PI3Kγ and mTOR respectively, shows cytotoxic effects in leukemia cell lines with CC50 of 4.37-9.44 uM.

Physicochemical Properties

M.Wt 356.43
Formula C18H24N6O2
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

3-(4-(1,4-Diazepan-1-yl)-6-morpholino-1,3,5-triazin-2-yl) Phenol

References

1. Aparecida E Silva C, et al. ACS Omega. 2026 Feb 5;11(6):9719-9733.

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