Welcome to Shanghai Probechem Biochemicals Co Ltd !Global Supplier of Chemical Probes, Inhibitors & Agonists.
Chemical Structure : LASV inhibitor 3.3
CAS No.: 554438-52-7
Catalog No.: PC-35712Not For Human Use, Lab Use Only.
LASV inhibitor 3.3 (LAMP1 inhibitor 3.3) is a specific inhibitor of Lassa fever virus (LASV, IC50=1.8 uM), inhibits LASV GP-mediated infection and cross-links to the LASV receptor, LAMP1, in cells.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 10 mg | $188 | In stock | |
| 25 mg | $298 | In stock | |
| 50 mg | $488 | In stock | |
| 100 mg | Get quote |
Bulk size, bulk discount!
E-mail: sales@probechem.com
Tech Support: tech@probechem.com
LASV inhibitor 3.3 (LAMP1 inhibitor 3.3) is a specific inhibitor of Lassa fever virus (LASV, IC50=1.8 uM), inhibits LASV GP-mediated infection and cross-links to the LASV receptor, LAMP1, in cells.
LASV inhibitor 3.3 does not inhibits the GP-mediated infection of LCMV, LuJo virus (LUJV) or Junin virus (JUNV), Ebola virus (EBOV) or vesicular stomatitis virus (VSV).
LASV inhibitor 3.3 inhibits LAMP1 binding to LASV GP, which is cholesterol-dependent and sensitive to 3.3 inhibition.
LASV inhibitor 3.3 is a competitive inhibitor of cholesterol binding to LAMP1.
| M.Wt | 471.645 | |
| Formula | C30H37N3O2 | |
| Appearance | Solid | |
| Storage |
|
|
| Solubility |
10 mM in DMSO |
|
| Chemical Name/SMILES |
N-(2-(4-benzhydrylpiperazin-1-yl)-2-oxoethyl)adamantane-1-carboxamide |
|
1. Wang MK, et al. PLoS Pathog. 2018 Sep 28;14(9):e1007322.
2. PCT Int. Appl. (2013), WO 2013022550 A2 20130214.
Copyright © 2022 probechem.com. All Rights Reserved. probechem Copyright
