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Chemical Structure : LCL204
Catalog No.: PC-61226Not For Human Use, Lab Use Only.
LCL204 is a small molecule that inhibits N-myristoyltransferase (NMT1) with IC50 of 8.7 uM, 10-fold enhanced inhibitory potency than LCL4.
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LCL204 is a small molecule that inhibits N-myristoyltransferase (NMT1) with IC50 of 8.7 uM, 10-fold enhanced inhibitory potency than LCL4.
LCL204 blocks Src myristoylation and Src localization to the cytoplasmic membrane.
LCL204 attenuates Src-mediated oncogenic signaling, suppresses cell-cycle progression, proliferation, and malignant growth of prostate cancer cells.
| M.Wt | 408.583 | |
| Formula | C23H40N2O4 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Kim S, et al. Cancer Res. 2017 Dec 15;77(24):6950-6962.
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