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LDN-209929 dihydrochloride

Chemical Structure : LDN-209929 dihydrochloride

CAS No.: 1784281-97-5

LDN-209929 dihydrochloride

Catalog No.: PC-23395Not For Human Use, Lab Use Only.

LDN-209929 dihydrochloride is a potent and selective haspin kinase inhibitor with IC50 of 55 nM, 180-fold selectivity over DYRK2.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

LDN-209929 dihydrochloride is a potent and selective haspin kinase inhibitor with IC50 of 55 nM, 180-fold selectivity over DYRK2.

Physicochemical Properties

M.Wt 405.76
Formula C17H19Cl3N2OS
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

1-Propanamine, 3-[(2-chloro-7-methoxy-9-acridinyl)thio]-, hydrochloride (1:2)

References

1. Gregory D Cuny, et al. Bioorg Med Chem Lett. 2010 Jun 15;20(12):3491-4.

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