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LED209

Chemical Structure : LED209

CAS No.: 245342-14-7

LED209 (LED-209)

Catalog No.: PC-45703Not For Human Use, Lab Use Only.

LED209 is a bacterial conserved membrane histidine sensor kinase QseC inhibitor.

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Biological Activity

LED209 is a bacterial conserved membrane histidine sensor kinase QseC inhibitor.
LED209 prevents autophosphorylation and inhibits QseC-mediated activation of virulence gene expression.
LED209 inhibits the virulence of several pathogens in vitro and in vivo in animals.

Physicochemical Properties

M.Wt 383.4872
Formula C19H17N3O2S2
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

DMSO: < 3.8 mg/mL

Chemical Name/SMILES

Benzenesulfonamide, N-phenyl-4-[[(phenylamino)thioxomethyl]amino]-

References

1. Rasko DA, et al. Science. 2008 Aug 22;321(5892):1078-80.

2. Spencer H, et al. J Bacteriol. 2010 Feb;192(3):714-24.

3. Xue XY, et al. Nanomedicine. 2015 Feb;11(2):329-39.

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