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Chemical Structure : LEI-106
Catalog No.: PC-20127Not For Human Use, Lab Use Only.
LEI-106 (LEI 106) is a potent, dual DAGL-α/ABHD6 inhibitor with Ki values of 0.7/0.8 uM, respectively.
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LEI-106 (LEI 106) is a potent, dual DAGL-α/ABHD6 inhibitor with Ki values of 0.7/0.8 uM, respectively.
LEI-106 is a sulfonamide derivative in the biochemical assay with an IC50 of 18 nM for DAGL-α and inhibited the hydrolysis of [14C]-sn-1-oleoyl-2-arachidonoyl-glycerol, the natural substrate of DAGL-α with Ki of 0.7 uM.
| M.Wt | 481.56 | |
| Formula | C26H27NO6S | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Freek J Janssen, et al. J Med Chem. 2014 Aug 14;57(15):6610-22.
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