Chemical Structure : LIT-001
CAS No.: 2245072-20-0
Catalog No.: PC-35699Not For Human Use, Lab Use Only.
LIT-001 (LIT001) is the first nonpeptide Oxytocin receptor (OXTR) agonist with EC50 of 55 nM, Emax=96%.
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LIT-001 (LIT001) is the first nonpeptide Oxytocin receptor (OXTR) agonist with EC50 of 55 nM, Emax=96%.
LIT-001 efficiently relieved social interaction deficits in Oprm1−/− mice, a mouse model of autism.
M.Wt | 531.679 | |
Formula | C28H33N7O2S | |
Appearance | Solid | |
Storage |
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Solubility |
10 mM in DMSO |
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Chemical Name/SMILES |
(S)-2-(Dimethylcarbamothioyl)-N-(2-methyl-4-(1-methyl1,4,5,10-tetrahydrobenzo[b]pyrazolo[3,4-e][1,4]diazepine-5- carbonyl)benzyl)pyrrolidine-1-carboxamide |
1. Frantz MC, et al. J Med Chem. 2018 Oct 11;61(19):8670-8692.
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