You are here:Home-Chemical Inhibitors & Agonists-GPCR-Oxytocin Receptor (OXTR)-LIT-001
LIT-001

Chemical Structure : LIT-001

CAS No.: 2245072-20-0

LIT-001 (LIT001)

Catalog No.: PC-35699Not For Human Use, Lab Use Only.

LIT-001 (LIT001) is the first nonpeptide Oxytocin receptor (OXTR) agonist with EC50 of 55 nM, Emax=96%.

Packing Price Stock Quantity
5 mg $98 In stock
10 mg $148 In stock
25 mg $258 In stock
50 mg Get quote
100 mg Get quote

Bulk size, bulk discount!

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

LIT-001 (LIT001) is the first nonpeptide Oxytocin receptor (OXTR) agonist with EC50 of 55 nM, Emax=96%.
LIT-001 efficiently relieved social interaction deficits in Oprm1−/− mice, a mouse model of autism.

Physicochemical Properties

M.Wt 531.679
Formula C28H33N7O2S
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

(S)-2-(Dimethylcarbamothioyl)-N-(2-methyl-4-(1-methyl1,4,5,10-tetrahydrobenzo[b]pyrazolo[3,4-e][1,4]diazepine-5- carbonyl)benzyl)pyrrolidine-1-carboxamide

References

1. Frantz MC, et al. J Med Chem. 2018 Oct 11;61(19):8670-8692.

Copyright © 2022 probechem.com. All Rights Reserved. probechem Copyright

Contact Us sales@probechem.com

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

  • *Product name:
  • *Applicant name:
  • *Email address:
  • *Organization name:
  • *Requested quantity:
  • *Country:
  • *Additional Information:

Get Quote

* Indicates a Required FieldYour information is safe with us.

  • *Product name:
  • *Applicant name:
  • *Email address:
  • *Organization name:
  • *Requested quantity:
  • *Country:
  • Additional Information: