Chemical Structure : LJ 001
CAS No.:
851305-26-5
LJ 001
(LJ001;LJ-001)
Catalog No.: PC-62050Not For Human Use, Lab Use Only.
LJ 001 (LJ-001, LJ001) is a broad-spectrum antiviral agent targeting entry of enveloped viruses, including influenza A, filoviruses, poxviruses, arenaviruses, bunyaviruses, paramyxoviruses, flaviviruses, and HIV-1.
Bulk size, bulk discount!
E-mail: sales@probechem.com
Tech Support: tech@probechem.com
Purity & Documentation Purity:
>98% (HPLC)
Biological Activity
LJ 001 ((LJ-001, LJ001) is a broad-spectrum antiviral agent targeting entry of enveloped viruses, including influenza A, filoviruses, poxviruses, arenaviruses, bunyaviruses, paramyxoviruses, flaviviruses, and HIV-1; specifically intercalates into viral membranes, irreversibly inactivates virions while leaving functionally intact envelope proteins, and inhibits viral entry at a step after virus binding but before virus-cell fusion; specifically inhibits virus-cell but not cell-cell fusion
Physicochemical Properties
|
M.Wt
|
327.42
|
|
Formula
|
C17H13NO2S2
|
|
Appearance
|
Solid
|
|
CAS No.
|
|
|
Storage
|
- Solide Powder
-
-20 °C 12 Months; 4°C 6 Months
|
- In Solvent
-
-80 °C 6 Months; -20°C 6 Months
|
|
Shipping
|
|
|
Solubility
|
10 mM in DMSO
|
|
Chemical Name/SMILES
|
(5Z)-5-[(5-phenylfuran-2-yl)methylidene]-3-prop-2-enyl-2-sulfanylidene-1,3-thiazolidin-4-one
|
References
1. Wolf MC, et al. Proc Natl Acad Sci U S A. 2010 Feb 16;107(7):3157-62.
2. Vigant F, et al. PLoS Pathog. 2013;9(4):e1003297.
3. Balmer BF, et al. J Virol. 2017 Jan 31;91(4). pii: e02181-16.
Contact Us
sales@probechem.com
