Chemical Structure : LJH-685
CAS No.:
1627710-50-2
LJH-685
(LJH 685, LJH685)
Catalog No. : PC-45677Not For Human Use, Lab Use Only.
LJH-685 is a potent and specific pan-RSK inhibitor with IC50s of 6 nM,5 nM and 4 nM for RSK1,RSK2 and RSK3 respectively.
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Purity & Documentation Purity:
>98% (HPLC) Select Batch: PC-4567701
Biological Activity
LJH-685 (LJH685) is a potent and specific pan-RSK inhibitor with IC50s of 6 nM,5 nM and 4 nM for RSK1, RSK2 and RSK3 respectively.
Physicochemical Properties
M.Wt
381.4185
Formula
C22H21F2N3O
Appearance
Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility
DMSO: ≥ 31 mg/mL
Chemical Name/SMILES
Phenol, 2,6-difluoro-4-[4-[4-(4-methyl-1-piperazinyl)phenyl]-3-pyridinyl]-
References
1. Jain R, et al. J Med Chem.
2. Aronchik I, et al. Mol Cancer Res.
3. Davies AH, et al. Oncotarget.
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