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Chemical Structure : LLC355
Catalog No.: PC-22339Not For Human Use, Lab Use Only.
LLC355 is a potent DDR1 degrader and autophagosome-tethering compound (ATTEC) with DC50 of 150.8 nM in NCI-H23 cells, induce DDR1 degradation via lysosome-mediated autophagy, potently suppresses cancer cell tumorigenicity, migration, and invasion.
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LLC355 is a potent DDR1 degrader and autophagosome-tethering compound (ATTEC) with DC50 of 150.8 nM in NCI-H23 cells, induce DDR1 degradation via lysosome-mediated autophagy, potently suppresses cancer cell tumorigenicity, migration, and invasion.
| M.Wt | 1133.72 | |
| Formula | C63H64ClF3N10O5 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Lianchao Liu, et al. J Med Chem. 2024 May 10. doi: 10.1021/acs.jmedchem.4c00162.
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